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Journal of Diabetes Research Volume 2020 ,2020-03-30
Combined Effect of Maternal Vitamin D Deficiency and Gestational Diabetes Mellitus on Trajectories of Ultrasound-Measured Fetal Growth: A Birth Cohort Study in Beijing, China
Research Article
Zheng Liu 1 Hui Liu 2 Xiangrong Xu 1 Shusheng Luo 1 Jue Liu 3 Chuyao Jin 1 Na Han 4 Hai-Jun Wang 1
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DOI:10.1155/2020/4231892
Received 2019-09-30, accepted for publication 2020-03-09, Published 2020-03-30
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摘要

Objective. Few studies have examined whether maternal 25(OH)D deficiency and gestational diabetes mellitus (GDM) jointly affect fetal growth. We aimed to examine the separate and combined effects of maternal 25(OH)D deficiency and GDM on trajectories of fetal growth. Methods. We established a birth cohort (2016-2017) with 10,913 singleton pregnancies in Tongzhou Maternal and Child Health Hospital of Beijing, China. Maternal 25(OH)D deficiency (serum 25OHD concentration0.05). Conclusion. Maternal 25(OH)D deficiency and GDM may jointly increase the risk of excessive fetal growth. Interventions for pregnancies with GDM may be more beneficial for those with 25(OH)D deficiency than those without regarding risk of excessive fetal growth, if confirmed in a large sample.

授权许可

Copyright © 2020 Zheng Liu et al. 2020
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

通讯作者

Hai-Jun Wang.Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China, pku.edu.cn.whjun@pku.edu.cn

推荐引用方式

Zheng Liu,Hui Liu,Xiangrong Xu,Shusheng Luo,Jue Liu,Chuyao Jin,Na Han,Hai-Jun Wang. Combined Effect of Maternal Vitamin D Deficiency and Gestational Diabetes Mellitus on Trajectories of Ultrasound-Measured Fetal Growth: A Birth Cohort Study in Beijing, China. Journal of Diabetes Research ,Vol.2020(2020)

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