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Evidence-Based Complementary and Alternative Medicine Volume 2020 ,2020-02-22
Functional MRI Investigation of Ultrasound Stimulation at ST 36
Research Article
Yarui Wei 1 Ling Mei 2 Xiaojing Long 2 Xiaoxiao Wang 1 Yanjun Diao 2 , 3 Benedictor A. Nguchu 1 Sheng Hu 1 Yanming Wang 1 Haibo Yu 2 , 3 Bensheng Qiu 1 , 3
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DOI:10.1155/2020/6794013
Received 2019-07-04, accepted for publication 2019-11-02, Published 2020-02-22
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摘要

Background. Clinical and experimental data suggest that ultrasound stimulation (US) at acupoints can produce similar effective treatment compared to manual acupuncture (MA). Although the brain activation to MA at acupoints is investigated by numerous studies, the brain activation to US at acupoints remains unclear. Methods. In the present work, we employed task state functional magnetic resonance imaging (fMRI) to explore the human brain’s activation to US and MA at ST 36 (Zusanli) which is one of the most commonly used acupoints in acupuncture-related studies. 16 healthy subjects underwent US and MA procedures in an interval of more than one week. On-off block design stimulation was used for the recording of fMRI-related brain patterns. Results. Both US and MA at ST 36 produced activations in somatosensory and limbic/paralimbic regions (postcentral gyrus, insula, middle prefrontal cortex, and anterior cingulate cortex). Only US at ST 36 produced a significant signal increase in the inferior parietal lobule and decrease in the posterior cingulate cortex, whereas MA at ST 36 produced a significant signal increase in the lentiform nucleus and cerebellum. Conclusions. Our results indicate that US may be a possible noninvasive alternative method to MA due to its similar activation patterns.

授权许可

Copyright © 2020 Yarui Wei et al. 2020
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

通讯作者

1. Xiaojing Long.Shenzhen Key Laboratory for MRI, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China, cas.cn.xj.long@siat.ac.cn
2. Bensheng Qiu.Centers for Biomedical Engineering, University of Science and Technology of China, Hefei 230027, Anhui, China, ustc.edu.cn;Shenzhen International TCM Training Center, Shenzhen Hospital of Traditional Chinese Medicine, Shenzhen 518002, China.bqiu@ustc.edu.cn

推荐引用方式

Yarui Wei,Ling Mei,Xiaojing Long,Xiaoxiao Wang,Yanjun Diao,Benedictor A. Nguchu,Sheng Hu,Yanming Wang,Haibo Yu,Bensheng Qiu. Functional MRI Investigation of Ultrasound Stimulation at ST 36. Evidence-Based Complementary and Alternative Medicine ,Vol.2020(2020)

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