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Acta Biomaterialia Odontologica Scandinavica Volume 5 ,Issue 1 ,2019-12-02
The effect of antimicrobial additives on the properties of dental glass-ionomer cements: a review
Review Articles
Tamer Tüzüner 1 Aleksandar Dimkov 2 John W. Nicholson 3 , 4
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Received 2018-7-9, accepted for publication 2018-10-10, Published 2019-12-02

Aim: The aim of this article is to review the literature on the use of antimicrobial additives in glass-ionomer dental cements.Method: An electronic search between 1987 and the end of 2017 was performed using PubMed, Web of Science and Google search engines with the terms glass-ionomer, glass polyalkenoate, antibacterial and antimicrobial as the key words. The search was refined by excluding the majority of references concerned with cement antimicrobial properties only. Extra papers already known to the authors were added to those considered.Results: A total of 92 relevant articles have been cited in the review of which 55 are specifically concerned with the enhancement of antibacterial properties of glass-ionomers, both conventional and resin-modified, with additives. In addition, information is included on the uses of glass-ionomers and the biological properties of the antibacterial additives employed. There are several reports that show that additives are typically released by diffusion, and that a high proportion is usually left behind, trapped in the cement. Additives generally increase setting times of cements, and reduce mechanical properties. However, smaller amounts of additive have only slight effects and the longer-term durability of cements appears unaffected.Conclusion: Modified glass-ionomer cements seem to be acceptable for clinical use, especially in the Atraumatic Restorative Treatment (ART) technique.


mechanical properties;antimicrobial;Glass-ionomer


© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.



Cetyl pyridinium chloride.

Benzalkonium chloride.


Fusidic acid.


John W. Nicholson.Bluefield Centre for Biomaterials, London, United Kingdom;Dental Physical Sciences, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdo.john.nicholson@bluefieldcentre.co.uk


Tamer Tüzüner,Aleksandar Dimkov,John W. Nicholson. The effect of antimicrobial additives on the properties of dental glass-ionomer cements: a review. Acta Biomaterialia Odontologica Scandinavica ,Vol.5, Issue 1(2019)



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