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FOOD AND AGRICULTURAL IMMUNOLOGY Volume 29 ,Issue 1 ,2018-01-01
The effect of dietary protein intake on immune status in pigs of different genotypes
Original Articles
Yulong Tang 1 , 2 , 3 Jianjun Li 2 Simeng Liao 2 Ming Qi 2 Xiangfeng Kong 2 Bie Tan 2 Yulong Yin 2 Jiaqi Wang 1
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DOI:10.1080/09540105.2018.1455812
Received 2018-1-12, accepted for publication 2018-3-16, Published 2018-3-16
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摘要

Little is known about the immune status of different pig breeds and the role of dietary protein intake. The present study, performed on 96 barrows (48 pure-bred Bama mini-pigs (fatty genotype) and 48 Landrace pigs (lean genotype)) randomly assigned to two dietary treatment groups (low- or adequate protein diet), with twenty-four24 individuals per treatment), evaluated the levels of immunoglobulins and cytokines in serum, and intestinal and splenic innate immunity on the two breeds. Data showed significant interactions between breed and diet for adaptive and innate immunity. Throughout the experiment, Landrace pigs showed significantly higher intestinal immune responses than Bama mini-pigs, and an adequate provision of dietary protein improved the expression of specific antibodies in early growth phases. These finding have important implication for improving the immune status of Landrace pigs, which are a major source of protein for humans.Abbreviations: BW: Body Weight; NRC diet: National Research Council diet; GB diet: Chinese conventional diet; CSFV: Classical Swine Fever Virus; IgG: Immunoglobulin G; IgM: Immunoglobulin M; SIgA: Secretory Immunoglobulin A.

关键词

cytokine;intestinal immunity;Landrace pigs;Bama mini-pig;Dietary protein

授权许可

© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

图表

Effects of dietary protein intake and breed on the levels of specific classical swine fever virus (CSFV) antibodies and immunoglobulins G and M in serum, in growth phases 1, 2, and 3. (a) concentration of CSFV antibodies; (b) concentration of IgG; (c) concentrations of IgM.Landrace pig/Chinese conventional (GB) diet group;Landrace pig/National Research Council (NRC) diet group;Bama mini-pig/GB diet group;Bama mini-pig/NRC diet group. Values are means (n = 8), and standard errors are represented by vertical bars. Effects were considered statistically significant if P < 0.05. S × D, strain × diet interaction.

Effects of dietary protein intake and breed on the intestinal secretion of secretory immunoglobulin A (SIgA) in growth phases 1, 2, and 3. (a) concentration of SIgA in jejunum; (b) concentration of SIgA in the lumen of jejunum.Landrace pig/ Chinese conventional (GB) diet group;Landrace pig/ National Research Council (NRC) diet group;Bama mini-pig/GB diet group;Bama mini-pig/NRC diet group; Values are means (n = 8), and standard errors represented by vertical bars. Effects were considered statistically significant if P < 0.05. S × D, strain × diet interaction.

通讯作者

1. Yulong Yin.Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center of Healthy Livestock, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, People’s Republic of Chin.yinyulong@isa.ac.cn
2. Jiaqi Wang.State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, People’s Republic of Chin.wang-jia-qi@263.net

推荐引用方式

Yulong Tang,Jianjun Li,Simeng Liao,Ming Qi,Xiangfeng Kong,Bie Tan,Yulong Yin,Jiaqi Wang. The effect of dietary protein intake on immune status in pigs of different genotypes. FOOD AND AGRICULTURAL IMMUNOLOGY ,Vol.29, Issue 1(2018)

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